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Mr M Supplements

L-Arginine + L-Citrulline by EVL Nutrition | 75 Scoops

L-Arginine + L-Citrulline by EVL Nutrition | 75 Scoops

$59.95 AUD
$59.95 AUD
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🧬 Overview: L-Arginine + L-Citrulline

These two amino acids are closely linked in the nitric oxide (NO) metabolic pathway, which regulates vascular tone, blood flow, and nutrient delivery.

  • L-Arginine → Direct precursor to nitric oxide (NO).

  • L-Citrulline → Converts into L-Arginine in the kidneys, thereby indirectly boosting NO levels.

When combined, they synergize to sustain higher and longer-lasting NO production than either amino acid alone.

 

⚕️ Mechanisms of Action

🧩 Nitric Oxide Pathway

  1. L-Arginine is converted by nitric oxide synthase (NOS) into nitric oxide (NO) and L-Citrulline.

  2. L-Citrulline then recycles back into L-Arginine, maintaining the supply.

  3. The result: Enhanced vasodilation, improved blood flow, and better nutrient/oxygen delivery to muscles and organs.

⚙️ Other Biological Effects

  • Improves ammonia clearance (important during exercise).

  • Supports creatine synthesis, growth hormone release, and immune function.

  • Enhances endothelial health and vascular elasticity.

💪 Potential Benefits

1. Exercise Performance

  • Increased endurance and strength: Better blood flow delivers oxygen and nutrients more efficiently.

  • Reduced muscle fatigue: Delays buildup of lactic acid and ammonia.

  • Improved recovery: Enhanced nutrient transport post-workout.

📖 Study: Bailey et al., J Appl Physiol (2015) — Citrulline supplementation improved cycling performance and reduced perceived exertion.

2. Cardiovascular Health

  • Enhances vascular function and lowers blood pressure via NO-mediated vasodilation.

  • May improve arterial stiffness and endothelial function in those with hypertension or metabolic syndrome.

📖 Study: Schwedhelm et al., Br J Clin Pharmacol (2008) — L-citrulline increases plasma L-arginine and improves endothelial function more effectively than arginine alone.

3. Erectile Function

  • Supports blood flow to erectile tissue via NO signaling (similar mechanism as PDE5 inhibitors like Viagra).

  • Works even better when paired with antioxidants (e.g., Pycnogenol, zinc, or ginseng).

📖 Study: Stanislavov et al., J Sex Marital Ther (2003) — Arginine + Pycnogenol improved erectile function in 80% of men after 1 month.

4. Immune and Wound Healing Support

  • Arginine enhances lymphocyte function, collagen deposition, and wound healing, particularly after surgery or trauma.

  • Citrulline’s recycling effect prolongs this benefit without as much GI distress as high-dose arginine.

 

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